Bolivian President Evo Morales has said he will expel the US Agency for International Development (USAID).
Mr Morales accused the agency of seeking to undermine his government.
USAID had been working in Bolivia for almost five decades, with the biggest part of its funding going to its counter-narcotics and military section.
In 2008, Mr Morales expelled the US ambassador and the US Drug Enforcement Administration (DEA) for allegedly conspiring against his administration.
Speaking at a rally in La Paz on Wednesday, the president said that there was “no lack of US institutions which continue to conspire against our people and especially the national government, which is why we’re going to take the opportunity to announce on this May Day that we’ve decided to expel USAID”.
On previous May Days, Mr Morales has announced the nationalisation of key industries, such as hydroelectric power and the electricity grid.
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